Science & technology | Treating dementia

A drug for Alzheimer’s disease that seems to work

It is not perfect. And it has side-effects. But it may be the real deal

Alzheimer's disease. Coloured single photon emission computed tomography (SPECT) scans of axial (horizontal) sections through a normal brain (top) and that of a patient with Alzheimer's disease (bottom). The colours show different levels of activity within the brain tissue, with red showing high activity and black very low activity. The Alzheimer's brain is less active. Alzheimer's is a degenerative brain disease and a common cause of dementia in the elderly. It causes memory loss, confusion and personality changes. Its causes are not known and there is no cure. SPECT scans use a gamma camera to detect radioactive traces, injected into the blood, that accumulate in areas of high metabolic activity.

Editor’s note: On January 6th America’s Food and Drug Administration approved lecanemab, to be marketed as Leqembi.

This article appeared in the Science & technology section of the print edition under the headline “Enter lecanemab”

China’s covid failure

From the December 3rd 2022 edition

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