The evidence to support medicalised gender transitions in adolescents is worryingly weak
The effectiveness and side-effects of the most common treatments are not well understood

PRISHA MOSLEY was 17 when she was first given testosterone in a clinic in North Carolina, after she had declared to her parents that she was a boy. She had struggled through her teen years with anorexia and depression after a sexual assault. Luka Hein had both breasts removed as a 16-year-old in Nebraska. Chloe Cole, in California, was a year younger when she had her double mastectomy. She had been on testosterone and puberty-blocking drugs since 13, also after a sexual assault.
This article appeared in the Briefing section of the print edition under the headline “Trans substantiation”
From the April 8th 2023 edition
Discover stories from this section and more in the list of contents
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He has yet to flatly defy a court order, which would initiate a constitutional crisis

America’s military supremacy is in jeopardy
To win future wars it needs new weapons, new suppliers and a new system of procurement
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And they are growing fast
Even in India, bureaucracy is being curtailed
Many small steps could make a big difference
Many governments talk about cutting regulation but few manage to
Yet radical deregulation is often a big boost to growth